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Yan-Hua Li Selected Research

fasudil (AT 877)

6/2020Fasudil inhibits the activation of microglia and astrocytes of transgenic Alzheimer's disease mice via the downregulation of TLR4/Myd88/NF-κB pathway.
1/2020Retraction: Effect of Fasudil on remyelination following cuprizone-induced demyelination.
1/2020Effect of Fasudil on remyelination following cuprizone-induced demyelination.
1/2019Nasal delivery of Fasudil-modified immune cells exhibits therapeutic potential in experimental autoimmune encephalomyelitis.
11/2018Therapeutic effect of Rho kinase inhibitor FSD-C10 in a mouse model of Alzheimer's disease.
1/2017Fasudil Enhances Therapeutic Efficacy of Neural Stem Cells in the Mouse Model of MPTP-Induced Parkinson's Disease.
1/2017FSD-C10, a Fasudil derivative, promotes neuroregeneration through indirect and direct mechanisms.
1/2017Multitarget Therapeutic Effect of Fasudil in APP/PS1transgenic Mice.
12/2016Synergistic and Superimposed Effect of Bone Marrow-Derived Mesenchymal Stem Cells Combined with Fasudil in Experimental Autoimmune Encephalomyelitis.
12/2015Role of Rho Kinase and Fasudil on Synaptic Plasticity in Multiple Sclerosis.
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Yan-Hua Li Research Topics

Disease

7Demyelinating Diseases (Demyelinating Disease)
01/2020 - 01/2017
7Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
07/2019 - 11/2012
6Infections
01/2022 - 04/2013
5Neoplasms (Cancer)
11/2021 - 09/2015
5Neuroinflammatory Diseases
01/2020 - 10/2012
4Lung Injury
01/2021 - 10/2017
4Multiple Sclerosis
01/2017 - 10/2014
3Alzheimer Disease (Alzheimer's Disease)
06/2020 - 01/2017
2Diarrhea
05/2022 - 01/2020
2Uterine Cervical Neoplasms (Cancer of the Cervix)
11/2021 - 12/2018
2Pulmonary Edema
01/2021 - 10/2017
2Pneumonia (Pneumonitis)
01/2021 - 09/2018
2Atrophy
01/2019 - 01/2019
2Inflammation (Inflammations)
01/2019 - 09/2018
2Virus Diseases (Viral Diseases)
08/2018 - 02/2010
2Persistent Infection
01/2018 - 02/2015
2Parkinson Disease (Parkinson's Disease)
01/2017 - 10/2015
2Pain (Aches)
01/2012 - 04/2008
1Critical Illness (Critically Ill)
05/2022
1Neoplasm Metastasis (Metastasis)
11/2021
1Rheumatoid Arthritis
02/2021
1Cushing Syndrome
02/2021
1Arthritis (Polyarthritis)
02/2021
1Type 2 Diabetes Mellitus (MODY)
01/2021
1Dyslipidemias (Dyslipidemia)
01/2021
1Postmenopausal Osteoporosis
10/2020
1Osteoporosis
10/2020
1Mitochondrial Diseases (Mitochondrial Disease)
02/2020
1Uterine Cervical Dysplasia
01/2020
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2020
1Ovarian Neoplasms (Ovarian Cancer)
01/2020
1Breast Neoplasms (Breast Cancer)
11/2019
1Stomach Neoplasms (Stomach Cancer)
08/2019
1Hemorrhage
01/2019
1Chronic Pancreatitis
01/2019
1Obesity
01/2019
1Fibrosis (Cirrhosis)
01/2019
1Pancreatitis
01/2019
1Mastitis
01/2019
1Lymphatic Metastasis
12/2018
1Glioma (Gliomas)
11/2018
1Cardiotoxicity
09/2018

Drug/Important Bio-Agent (IBA)

14fasudil (AT 877)IBA
06/2020 - 11/2012
7Proteins (Proteins, Gene)FDA Link
05/2022 - 01/2017
7rho-Associated KinasesIBA
01/2019 - 10/2014
4CuprizoneIBA
01/2020 - 01/2019
4Therapeutic UsesIBA
01/2019 - 01/2017
3Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 02/2015
3fibroblast growth factor 21IBA
02/2021 - 01/2019
3CytokinesIBA
02/2021 - 03/2016
3Cisplatin (Platino)FDA LinkGeneric
01/2020 - 11/2018
2Peptides (Polypeptides)IBA
05/2022 - 02/2010
2hydroxyfasudilIBA
01/2020 - 01/2019
2Myelin-Oligodendrocyte GlycoproteinIBA
01/2019 - 03/2015
2Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2019 - 01/2017
2MicroRNAs (MicroRNA)IBA
11/2018 - 09/2015
2XenobioticsIBA
09/2018 - 01/2018
2AtrazineIBA
09/2018 - 01/2018
1Long Noncoding RNAIBA
11/2021
1VimentinIBA
11/2021
1Biological ProductsIBA
11/2021
1Dexamethasone (Maxidex)FDA LinkGeneric
02/2021
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2021
1youguiIBA
10/2020
1Sirtuin 1IBA
02/2020
1Sirtuin 3IBA
02/2020
1ResveratrolIBA
02/2020
1Ciliary Neurotrophic Factor (CNTF)IBA
01/2020
1Black-GoldIBA
01/2020
1Dosage Forms (Dosage Form)IBA
01/2020
1Myelin Basic ProteinIBA
01/2020
1Small Interfering RNA (siRNA)IBA
01/2020
1Luxol Fast Blue MBS (Luxol fast blue)IBA
01/2020
1CateninsIBA
01/2020
1Nerve Growth Factor (NGF)IBA
01/2020
1p38 Mitogen-Activated Protein KinasesIBA
11/2019
1DNA-Activated Protein KinaseIBA
11/2019
1Indicators and Reagents (Reagents)IBA
08/2019
1DNA (Deoxyribonucleic Acid)IBA
08/2019
1GTP Phosphohydrolases (GTPases)IBA
07/2019
13- (2,4- dichloro- 5- methoxyphenyl)- 2- sulfanyl- 4(3H)- quinazolinoneIBA
07/2019
1Dynamins (Dynamin)IBA
07/2019
1AmylasesFDA Link
01/2019
1Sorafenib (BAY 43-9006)FDA Link
01/2019
1Anti-Infective Agents (Microbicides)IBA
01/2019
1Type VI Secretion SystemsIBA
01/2019
1CollagenIBA
01/2019
1Sodium Glutamate (Accent)IBA
01/2019
1Interleukin-6 (Interleukin 6)IBA
01/2019
1myelin oligodendrocyte glycoprotein (35-55)IBA
01/2019
1Arginine (L-Arginine)FDA Link
01/2019
1Paclitaxel (Taxol)FDA LinkGeneric
12/2018
1Sevoflurane (Ultane)FDA LinkGeneric
09/2018

Therapy/Procedure

3Drug Therapy (Chemotherapy)
01/2020 - 06/2017
3Therapeutics
01/2018 - 09/2009
2Enteral Nutrition (Feeding, Tube)
05/2022 - 08/2014
2One-Lung Ventilation
01/2021 - 10/2017
2Percutaneous Coronary Intervention
01/2019 - 12/2012
2Electroacupuncture
12/2011 - 04/2008
1Chinese Traditional Medicine (Traditional Chinese Medicine)
10/2020